Bioengineering

 The Spark WaveTM therapy has evolved into a simultaneously effective and gentle alternative to conservative treatment methods in the fields of wound care, orthopaedics /  traumatology and urology within the last  years. The non-invasive therapy has been approved by millions of patients. It is known to be safe and easily tolerable.

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Tissue Regeneration

Recent scientific results show that Spark WaveTM energy re-initiates the stagnating healing process in a subacute and chronic state and initiates a quick and effective healing process in an acute stadium. Spark WavesTM are special shock waves that are characterized by a brief rise time and high pressure. They influence the cell membrane permeability within the affected tissue and activate a cascade of bio-chemical regeneration mechanisms on cellular level.

Numerous clinical studies confirm that Spark WavesTM induce amongst others the following biological reactions on cellular level:

  • the body´s own production of growth factors such as VEGF, eNOS, PCNA etc.
  • the new promotion of blood vessels (angiogenesis & vasculogenesis)
  • an improved blood flow and cell proliferation as well as
  • the migration of stem cells.

In addition, MTS Spark WavesTM unfold in vitro a bactericidal effect which strongly minimizes the amount of germs and bacteria in the affected tissue. The combination of all mentioned factors stimulates the healing process and ultimately promotes the development of new and healthy tissue (Tissue Regeneration).

Increased production of growth factors

Spark WavesTM initiate the increased production of pro-angiogenic growth factors such as VEGF, eNOS, PCNA etc. which leads to an intensified cell proliferation and therefore to tissue regeneration of the treated tissue. A higher production of growth factors can be proven already within a few hours and up to several days after Spark WaveTM treatment.

Angiogenesis & Vasculogenesis

Spark WavesTM initiate the increased production of pro-angiogenic growth factors that activate the growth of new blood vessels by means of pullulation and separation processes from already existing blood vessels respectively. The growth factor VEGF (vessel endothelial growth factor) also plays an important role in the vasculogenesis. This means the complete re-production of blood vessels from endothelial progenitor cells. Angiogenesis as well as vasculogenesis strongly contribute to an improved blood supply of the affected tissue